Health claim
“NAD+ precursors such as nicotinamide riboside (NR) improve mitochondrial function and may delay age‑related decline.”
Claim checked — mixed / earlyHigh risksupplements
Evidence Summary
Some evidence supports this, but findings are inconsistent or limited in scope.
Preclinical studies show NAD+ precursors can enhance mitochondrial function and mitigate age‑related decline in animal models, but human trials provide limited and inconsistent evidence, with modest effects at best.
Extracted from
333 ‒ Longevity roundtable—the science of aging, geroprotective molecules, & lifestyle interventionsPeter Attia MD
A roundtable discussion featuring Peter Attia and three experts examines current scientific understanding of aging, potential geroprotective compounds, and lifestyle strategies for longevity.
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