Health claim
“Resistance training that reaches muscular failure two times per week can increase NAD+ levels, which are associated with longevity.”
Claim checked — weak evidenceMedium riskexercise
Evidence Summary
Limited or low-quality evidence — treat with caution.
Exercise can modestly raise NAD+ precursors, yet the magnitude and impact on human longevity remain uncertain.
Extracted from
How to Exercise to Live Longer | Lifespan with Dr. David Sinclair - S2, Ep. 5David Sinclair
The episode discusses Dr. David Sinclair's perspective on exercise strategies that may support longer, healthier lives, highlighting mechanisms of cellular aging and practical workout recommendations.
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